AFP FIA Rapid Test

PRODUCT INTRODUCTION

Intended use

This AFP FIA Rapid Test is designed for in vitro quantitative detection of AFP in human serum or plasma samples. It’s for professional only.

Summary

Alpha-fetoprotein(AFP) is a glycoprotein that belongs to the albumin family and is mainly synthesized by fetal liver cells and yolk sac. AFP has a high concentration in fetal blood circulation, and it decreases after birth. AFP is basically replaced by albumin in 2-3 months after birth. It is difficult to detect in blood, so the content in adult serum is extremely low. AFP has many important physiological functions, including transport function, bidirectional regulation function as a growth regulator, immunosuppression, lymphocyte induction of apoptosis and so on.

Principle

The AFP FIA Rapid Test adopts microfluidic fluorescence immunoluminescence method, Liquid reaction system helps get more accurate AFP test results in 10 minutes.

Why Test AFP?

Measurement of AFP is generally used in two clinical contexts. First, it is tested in pregnant women by the analysis of maternal blood or amniotic fluid as a screening test for some developmental abnormalities,AFP gradually decreases to undetectable after birth.

Second, AFP is one of the tumor markers. It is often detected clinically by collecting blood. It is mainly used for auxiliary diagnosis of primary liver cancer and other malignant tumors. However, if liver cells or gonadal embryonic tissues become cancerous, the synthesis of AFP will increase, leading to an increase in its content in serum.

So AFP is used as a biomarker with associated elevated level in human serum in some of these diseases below:

· Developmental birth defects associated with elevated AFP in amniotic fluid and maternal serum

  Omphalocele,Gastroschisis,Neural tube defects,intrauterine death, neural tube defects, anencephaly and Spina bifida, etc.

· Tumors associated with elevated AFP

   Hepatocellular carcinoma

   Metastatic disease affecting the liver

   Nonseminomatous germ cell tumors

   Yolk sac tumor

· Other conditions like ataxia telangiectasia.

Advantage

Accurate Core technology includes Microfluidic,TRFIA,Inkjet freeze-drying technology makes the reacion system liquid and react more sufficient,providing a more accurate AFP report.

Easy to use 

Sample to results in 3 steps.

Fast

The react time is 10 minutes.

PRODUCT PARAMETER

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