Fluorescent Immunoassay PAMG-1 POCT Kit

Intended use

This Fluorescent Immunoassay PAMG-1 POCT Kit is designed for in vitro quantitative detection of PMAG-1 in vaginal secretions samples. It’s for professional only.

Summary

PAMG-1, the abbreviation of placental alpha microglobulin-1,was discovered in the Soviet Union in the 1970s and remained relatively unknown until much later. It is a glycoprotein synthesized, secreted by lymphocytes and expressed by cells in the decidua region of the placenta. During pregnancy, PAMG-1 is secreted into the fluid in large quantities by amniotic membranes . Its level in amniotic fluid is relatively high and its content in cervical secretions of pregnant women is low. Therefore, PAMG-1 was chosen as a marker for rupture of membranes due to its unique properties, e.g. measurement of cervical cervix using selected antibodies when membranes are intact - Low basal concentration of vaginal secretions.

Principle

The fluorescent immunoassay PAMG-1 POCT kit adopts microfluidic fluorescence immunoluminescence method, which helps get more accurate PAMG-1 level results in 10 minutes.

Why Test PAMG-1 ?

PAMG-1 is a major protein in the amniotic fluid of pregnant women. When premature rupture of membranes occurs in pregnant women, PAMG-1 in the amniotic fluid will leak into the cervix and vagina of pregnant women along with the rupture of the membranes; but in The concentration in vaginal and cervical secretions of normal pregnant women is very low. Therefore, PAMG-1 has become a detection marker for clinical diagnosis of premature rupture of membranes. In addition, other secretions and foreign bodies in the pregnant woman's cervix, such as: vaginitis, urine, semen and mucus, etc. will not affect the test results, and have very high sensitivity and specificity.

The detection of PAMG-1 by the fluorescent immunoassay PAMG-1 POCT kit in cervical secretions of pregnant women has nothing to do with the actual gestational age of pregnant women. It has very high sensitivity and specificity for pregnant women who are about to go to clinical practice or pregnant women who are not in labor, and the clinical diagnostic value is also very, very high.

Q: What does <100 mean?

A:If the test result is less than 100, It means that the sample is judged as PAMG-1 negative .

Q: Is it 100% accurate?

A: Yes, it’s definitely accurate.VACURE regards product quality as the life of the company.

Q: Are there other markers to detect premature?

A: Yes,we offer fFn ,IGFBP-I,PLGF and SFLT-1,β-HCG to detect On-demand.

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