The Fluorescence immunoassay Cardiac Markers Kit is of great significance for the diagnosis of myocardial infarction, the evaluation of the effect of thrombolytic therapy, the evaluation of re-infarction or the extent of infarction and the degree of risk.
Summary
Myoglobin is an oxygen-binding heme protein that exists in the myocardium and is the earliest myocardial protein marker that abnormally increases after myocardial injury. Mainly present in cardiac and skeletal muscle, released into blood when skeletal muscle and cardiac muscle are damaged (acute myocardial infarction), excessive exercise and muscle disease. In acute myocardial infarction, the concentration of myoglobin in serum can increase within 1-3 hours of the initial stage of chest pain, reach the highest level in 4-8 hours, and return to normal around 24 hours-36 hours. The concentration of myoglobin in the blood is effective for monitoring the diagnosis and treatment of acute myocardial infarction, and can be used as an indicator of coronary artery recanalization in thrombolytic therapy. The concentration of myoglobin reaches the highest level after 30 minutes to 2 hours. Myoglobin concentration can be used as an early diagnostic indicator of myocardial infarction.
Troponin is a complex of three proteins, troponin T, troponin C, and troponin I, which is only present in cardiac tissue. Cardiac troponin generally increases gradually in peripheral blood 4-8h after myocardial injury, and reaches its peak at 8-16h. Increased cardiac troponin can still be detected in peripheral blood 7-10 days after myocardial injury. There are also detection systems that detect troponin T. cTnI/cTnT is unanimously rated as a highly specific and highly sensitive marker for the diagnosis of acute myocardial infarction by the American and European Heart Associations. Since cTnI/cTnT is specific to the myocardium, patients with chest pain 4 hours after the onset of cTnI/cTnT can be directly detected by cTnI/cTnT, and the elevated serum/plasma level has diagnostic specificity. Early diagnosis of AMI can win valuable treatment for patients time.
Creatine kinase isoenzyme (CK-MB) is an important indicator for early diagnosis of acute myocardial infarction and myocardial necrosis. CK-MB mainly exists in the myocardium; especially for acute myocardial infarction and recurrent myocardial infarction without Q wave in the electrocardiogram, the increase of CK-MB in serum has a decisive role in diagnosis. However, certain non-myocardial factors can also lead to elevated CK-MB, which can be identified by detecting CK-MB mass. 3-8 hours after the onset of symptoms of acute myocardial infarction or myocarditis, CK-MB in serum increases significantly, reaches the peak value at 8-24 hours (up to 10-20 times the upper limit of the reference interval), and returns to normal levels after 3 days without complications. CK-MB continued to increase 72 hours after the onset of chest pain, indicating that the myocardial necrosis in the patient continued to deteriorate. Serum CK-MB is not affected by striated muscle injury factors, and AMI can be diagnosed within 72 hours after the onset of chest pain; it has a high specificity (98%) for diagnosing AMI and re-MI after admission.
In summary, this Fluorescence immunoassay Cardiac Markers Kit can be used to diagnose myocardial infarction, myocarditis, and to determine the presence of myocardial injury. Once the disease is diagnosed, patients need to be treated as early as possible.
FAQ
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A: we offer 100 Tests, 50 Tests, 25 Tests, 10 Tests, 5 Tests, 100 Tests (N-QC), 50 Tests (N-QC), 25 Tests (N-QC), 10 Tests (N-QC), 5 Tests (N-QC).
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A: Yes.Please contact us.
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