Myeloperoxidase (MPO) Test Kit

Intended use

This device is intended to be used for the in vitro quantitative determination of myeloperoxidase (MYO) in human whole blood, serum or plasma. And it is for professional use only, not for self-testing of untrained individuals, nor for near-patient testing.

Summary

Myeloperoxidase (MPO) mainly exists in the azurophilic granules of neutrophils or monocytes. During inflammation, neutrophils degranulate and release MPO. It can lead to instability or even rupture of coronary atherosclerotic lesions, to make exposure of subendothelial collagen tissue, followed by platelet adhesion and aggregation and thrombosis, resulting in acute coronary syndrome (ACS) and severe myocardial irreversible ischemic damage. The pathogenic mechanism of MPO includes oxidizing low-density lipoprotein, enhancing the pathogenic effect of low-density lipoprotein, accelerating the formation of atherosclerotic plaques; generating free radicals and various reactive substances to promote coronary atherosclerotic plaques instability and rupture; oxidizing high-density lipoprotein to make apolipoprotein A1 lose the function of reverse cholesterol transport, resulting in intracellular deposition of cholesterol; promoting the formation of atherosclerotic plaques and plaque instability, causing ACS . A large number of clinical studies have shown that the changes of MPO levels are closely related to the onset of acute myocardial infarction (AMI), and serum MPO levels in ACS patients are significantly increased, so MPO can be used as a new predictor of cardiovascular adverse events in ACS patients, especially in the presence of low troponin levels, MPO is able to identify those high-risk patients who will develop MACE.

The current clinical methods for detecting MYO include chemiluminescence, immunochromatography and so on.

Hospitals

Laboratory

Clinics

Ambulance

Q: Are the results of CRP, SAA whole blood and peripheral blood the same?

A: Our laboratory big data test results show that the test results of CRPSAA on whole blood and fingertip blood are consistent. In the process of detecting fingertip blood, the inspecting doctor should try to avoid inhaling impurities such as subcutaneous tissue, which may lead to deviations in the test results.

This question is placed under the two products of CRP and SAA.

Q: Is it possible to add emergency testing to our instrument in the middle of the testing process?

A: LYOFIA 100, DISKFLU 1000, these two instruments can achieve.

This question is placed under LYOFIA 100, DISKFLU 1000, these two products.

Q: Does whole blood sample hemolysis, lipidemia, or fibrin, etc., have any effect on the product?

A: There will be an impact, so be careful.

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