Intended use

This device is intended to be used for the in vitro quantitative determination of Interleukin-6 (IL-6) in human serum or plasma. And it is for professional use only, not for self-testing of untrained individuals, nor for near-patient testing.

Summary

Interleukin-6 is a pleiotropic cytokine with a wide range of functions. It is an intermediary of the immune system. It is expressed in single cells and contains 212 amino acids. It can be cut to form a mature protein of 184 amino acids with a molecular weight of about 22-27 kDa. A large number of studies have found that interleukin-6 not only has physiological activities on B cells, but also has physiological effects on T cells, hematopoietic stem cells, liver cells, and brain cells. Interleukin-6 is rapidly produced during acute inflammatory responses to trauma, surgery, stress, infection, and other conditions. Interleukin-6 levels in surgical patients can predict the occurrence of surgical complications. Serial detection of serum or plasma interleukin-6 levels in intensive care (ICU) patients can effectively assess the severity of systemic inflammatory response syndrome (SIRS), sepsis, and the prognosis of septic shock. Interleukin-6 also acts as an early warning indicator of sepsis.

The current clinical methods for detecting IL-6 include chemiluminescence, immunochromatography and so on.

PRODUCT PARAMETER

TEST INFORMATION
Method	Microfluidic Fluorescent Immunoassay	Test	LYOFIA® IL-6
Format	Cassette	Reaction Time	10 min
Linearity	2～3000pg/mL	Reference Interval	≤7pg/mL
Sample	S / P	Certificate	CE/NMPA

ORDERING
Cat. No.	LMFMIL25	Applicable analyzer	LYOFIA-I, LYOFIA 8,	Kit Size	25T
Cat. No.	LAFMIL25	Applicable analyzer	LYOFIA 100 (Full-Automatic)	Kit Size	25T