Definition: Also known as peroxidase, it’s a heme protease of heme prosthetic group, and is one of the members of the heme peroxidase superfamily.
It exists in the hyperchromatin granules of myeloid cells (mainly neutrophils and monocytes) and is a specific marker of myeloid cells. #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
Function: Kills microorganisms which phagocytosed by cells and can be released outside cells to destroy a variety of target matter, such as tumor cells, platelets, NK cells, protozoa, toxins, etc., and play a role in the production and regulation of inflammatory responses in the body; #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
Promotes the formation of AS lesions, MPO promotes plaque formation and increased instability by generating free radicals and a variety of reactive substances, accelerates the progression of AS, and then causes various complications such as acute coronary syndrome (ACS). #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
Clinical application of MPO:
1. A large number of literature data show that MPO can be used as a predictor of coronary heart disease and a prognostic indicator of acute coronary syndrome; Elevated MPO indicates that patients have coronary inflammation and unstable plaques, but the blood vessels are not completely blocked and do not cause myocardial necrosis. Therefore, MPO can identify unstable plaques early and is one of the inflammatory markers for early diagnosis of ACS; #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
2. As a novel inflammatory marker to predict ACS, MPO can identify the risk of future adverse cardiovascular events in cardiac troponin T (cTnT)-negative ACS patients; #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
3. Foreign literature pointed out that MPO baseline level can independently predict the risk of sudden cardiac adverse events (myocardial infarction, reinfarction, revascularization or death) in the next 30 days to 6 months; #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
4. MPO can identify low-level C-reactive protein (CRP-negative) patients with poor prognosis in ACS; #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
5. Predict the future risk of cardiovascular disease in healthy people over 35 years of age. MPO independently predicts future cardiovascular disease risk in healthy individuals rather than C-reactive protein and other inflammatory markers. #Cardiac Marker POCT#Myeloperoxidase (MPO) test Kit#MPO test kit
