Only present in the Myocardium, not found in other tissues.
Features: Long diagnostics window period、High Specificity
Specificity: 98%; Sensitivity: 97%
(1) At the 1999 meeting on the standardization of myocardial injury markers, it was agreed that cTnI was more specific than cTnT (98% vs. 96%);
(2) cTnI monoclonal antibody replaced CK-MB as the new "gold standard" after the 1990s.
Peak in Blood: 4-8 hours start to rise; 12-24 (16) hours peak; 5-10 days back to normal
Linearity: 0.16 ng/ml-32ng/ml
Reference Interval: 0.16 ng/ml
During fetal development, skeletal muscle injury and regeneration, renal insufficiency on long-term dialysis and some myopathy patients, cTnT in blood is elevated, while cTnI is normal at this time, and cTnI has superior myocardial specificity than cTnT. #hs-cTnI #Cardiac Marker#AMI-3
#High sensitive-Cardiac Troponin I #POCT