Basic Information on Glycated Hemoglobin

Glycated hemoglobin (HbA1c) is the product of the combination of hemoglobin in red blood cells and sugars (mainly glucose) in serum through a non-enzymatic reaction. The non-enzymatic reaction to form glycated hemoglobin is continuous, slow and irreversible. Therefore, the content of glycated hemoglobin is determined by the past rather than immediate blood glucose concentration, and whether it is fasting before the test, whether to inject insulin, whether to take hypoglycemic drugs, etc. Factors are irrelevant. It is generally believed that the concentration of glycated hemoglobin can effectively reflect the average blood glucose level of the past 8 to 12 weeks. Glycated hemoglobin is composed of HbA1a, HbA1b, and HbA1c, of which HbA1c accounts for about 70%, and the structure is relatively stable.