CRP is not only a non-specific inflammatory marker, but also directly involved in cardiovascular diseases such as inflammation and atherosclerosis, and is the most powerful predictor and risk factor for cardiovascular diseases. The interaction of CRP with complement C1q and FcTR enables it to exhibit many biological activities, including host defense against infection, phagocytosis and regulation of inflammatory responses. Binds to damaged cells, apoptotic cells and nuclear antigens, making it also play an important role in autoimmune diseases
