(1) A variety of acute inflammation, tissue damage, myocardial infarction, surgical trauma, radiation injury and other diseases rapidly increase within a few hours after the onset, and have a tendency to increase exponentially. When the lesions improved, they quickly returned to normal, and the increase was positively correlated with the degree of infection. The CRP level of patients after surgery increases, and the CRP level should decrease 7 to 10 days after surgery. If CRP does not decrease or increases again, it may be complicated by infection or thromboembolism.
(2) CRP is closely related to other inflammatory factors, such as total number of leukocytes, erythrocyte sedimentation rate and polymorphonuclear leukocytes. There is also a positive correlation with WBC. Plays an active role in the inflammatory response, giving the body non-specific resistance. When the patient's disease occurs, it can rise earlier than WBC, and it returns to normal quickly, so it has a very high sensitivity.
(3) Help to identify the type of respiratory tract infection. CRP can be used for the differential diagnosis of bacterial and viral infections: during bacterial infection, the level of CRP increases; while during viral infection, CRP does not increase or increases slightly, so the CRP value can help doctors identify the type of respiratory tract infection. of medication and treatment. [2]
(4) CRP is elevated in patients with malignant tumors. For example, the combined detection of CRP and AFP can be used for the differential diagnosis of liver cancer and benign liver diseases, and it can be used to judge the efficacy and prognosis of liver cancer. CRP increased before surgery and decreased after surgery, and its response was not affected by radiotherapy, chemotherapy and corticosteroid therapy, which is helpful to assess tumor progression.
(5) Evaluate the severity of acute pancreatitis. When CRP is higher than 250 mg/L, it indicates extensive necrotizing pancreatitis.
(6) The detection of CRP by the supersensitive latex enhanced method can improve the sensitivity of the measurement and can be used to predict the risk of coronary heart disease and myocardial infarction